Copper associated childhood cirrhosis.

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Copper associated childhood cirrhosis.

Several papers have reported severe liver disease in association with massive hepatic copper accumulation, which do not seem to be either of the recognised copper associated liver diseases, namely Wilson's disease and Indian childhood cirrhosis. A further case is reported in which novel copper kinetic studies were carried out using the stable isotope 65Cu, showing that this patient did not suff...

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Copper in urine and hair in Indian childhood cirrhosis.

In advanced Indian childhood cirrhosis (ICC) urine copper concentration was higher (range 416-103,448 mg/g creatinine) than in other hepatic diseases (range 67-10,303 mg/g creatinine). In early ICC urine copper concentration was more modestly raised (1188-9470 mg/g creatinine), but rose to high values (2222-42,819 mg/g creatinine) after a single dose of penicillamine 20 mg/kg. A post-penicillam...

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Serum Copper and Hepatic Copper in Chronic Liver Diseases with Particular Reference to Indian Childhood Cirrhosis

Sixty five patients (20 children and 45 adults of both sexes) having hepatomegaly were subjected to serum copper, hepatic copper and hepatic cuproprotein analysis from October 1982 through September 1983. Higher levels of serum copper were encountered in 17/20 children suffering from Indian Childhood Cirrhosis (ICC), values ranging from 151 ug/dl to 350 ug/dl. Hypercupremia was also detected in...

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Indian Childhood Cirrhosis: Case Report and Pediatric Diagnostic Challenges

Introduction: Indian childhood cirrhosis is a chronic liver disease usually seen in paediatric age group and is unique to the Indian subcontinent. The definitive causative factor for the disease is not found till now but excess copper ingestion has been associated with it.Case presentation: An Indian origin one and half year old premorbidly normal male child presented with history of gradual di...

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Indian childhood cirrhosis.

Neviasa JS. Adhesive capsulitis of the shoulder. A study of the pathological findings in periarthritis of the shoulder. J Bone J'oint Surg 1945 ;27 :211-22. 2 Bruckner FE, Nye CJS. A prospective study of adhesive capsulitis of the shoulder ("frozen shoulder") in a high risk population. Q 7 Med 1981; 198:191-204. 3Wright V, Haq AMMM. Periarthritis of the shoulder. II. Radiological features. Ann ...

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ژورنال

عنوان ژورنال: Gut

سال: 1994

ISSN: 0017-5749

DOI: 10.1136/gut.35.10.1497